Advanced Seminars in Behavioral Neuroendocrinology - Molecular Mechanisms of Affect
Summers
SN2ACKS: Systems and Neuroscience Networks Advanced Communication of Knowledge Seminars
formerly: Advanced Seminars in Behavioral Neuroendocrinology

Molecular Mechanisms of Affect
Fall 2020
GFP
Date Speaker
streaming video
room Title of the 1o Journal Paper Authors

year

journal

volume:

pages

Aug 28 Cliff UCL
173
Story Telling is at the heart of Science
Seminar Success Guide
Intinerary, Schedule and Organization
CH Summers 2020
Sept 4 Cliff UCL
173
How to chose a paper, What makes a good talk, Guide to Seminar Design
Seminar Success Guide Organization
Full USD Syllabus for the Seminar course Molecular Mechanisms of Affect
CH Summers 2020
September 18 Jazmine
Yaeger
UCL
173
Gephyrin palmitoylation in basolateral amygdala mediates the anxiolytic action of benzodiazepine

Background papers:
Fang et al., 2018 Frontiers in Neuroscience 12:387doi: 10.3389/fnins.2018.00387 1-13 Traumatic stress produces distinct activations of GABAergic and glutamatergic neurons in amygdala

Saha et al., 2017 Neuropsychopharmacology 42:473–484 GABAergic synapses at the axon initial segment of basolateral amygdala projection neurons modulate fear extinction
Z-C Shen
P-F Wu
F Wang
Z-X Xia
Q Deng
T-L Nie
S-Q Zhang
H-L Zheng
W-H Liu
J-J Lu
S-Q Gao
X-P Yao
L-H Long
Z-L Hu
J-G Chen

2018
Biological
Psychiatry

85:
202–213
September 25 Chinenye
Izuegbunam
UCL
173
The gut microbiota metabolite indole increases emotional responses and adrenal medulla activity in chronically stressed male mice

Background papers:
Zheng et al., 2016 Molecular Psychiatry 21:786–796 Gut microbiome remodeling induces depressive-like behaviors through a pathway mediated by the host’s metabolism

Kelly et al., 2016 Journal of Psychiatric Research 82: 109-118 Transferring the blues: Depression-associated gut microbiota induces neurobehavioural changes in the rat
H-D Mir
A Milman
M Monnoye
V Douard
C Philippe
A Aubert
N Castanon
S Vancassel
NC Guérineau
L Naudon
S Rabot

2020
Psychoneuro-
-endocrinology

119:
104750: 1-10
October 2 Kevin
Krupp
UCL
173
Sphingosine-1-phosphate receptor 3 in the medial prefrontal cortex promotes stress resilience by reducing inflammatory processes

Background papers:
Couch et al., 2013 Brain, Behavior, and Immunity 29:136–146 Microglial activation, increased TNF and SERT expression in the prefrontal cortex define stress-altered behaviour in mice susceptible to anhedonia

McKlveen et al. 2013 Biological Psychiatry 74:672–679 Role of prefrontal cortex glucocorticoid receptors in stress and emotion
BF Corbett
S Luz
Jay Arner
J Pearson-Leary
A Sengupta
D Taylor
P Gehrman
R Ross
S Bhatnagar

2019
Nature
Communications

10:
3146: 1-13
October 9 Chad
Ryan
UCL
173
Dorsal hippocampus ERK2 signaling mediates anxiolytic-related behavior in male rats

Background papers:
Iñiguez et al., 2019 Behavioral Neuroscience 133: 225–231 Upregulation of hippocampal extracellular signal-regulated kinase (ERK)–2 induces antidepressant-like behavior in the rat forced swim test


Aringhieri et al., 2017 European Neuropsychopharmacology 27: 383–398 Clozapine as the most efficacious antipsychotic for activating ERK 1/2 kinases: Role of 5-HT2A receptor agonism
JA Sierra-Fonseca
LF Parise
Francisco J. Flores-Ramirez
EH Robles
I Garcia-Carachure
SD Iñiguez
2019
Chronic
Stress
3:
1–7
October 16 Jason
Gale
UCL
173
Mechanisms of memory impairment induced by Orexin-A via Orexin 1 and Orexin 2 Receptors in Post-traumatic Stress Disorder Rats

Background papers:
Zhan et al., 2019 Journal of Cellular and Molecular Medicine 23:6822–6834 Molecular mechanism of tumour necrosis factor alpha regulates hypocretin (orexin) expression, sleep and behaviour

Yu et al., 2017 Brain, Behavior, and Immunity 73:317-326 Microglial production of TNF-alpha is a key element of sustained fear memory
D Han
F Han
Y Shi
S Zheng
L Wen

2020
Neuroscience

432:
126–136
October 23 Ben
Onserio
UCL
173
Seasonal changes in NRF2 antioxidant pathway regulates winter depression-like behavior

Background papers:
Yao et al., 2016 Scientific Reports 6: 30659: 1-13 Role of Keap1-Nrf2 signaling in depression and dietary intake of glucoraphanin confers stress resilience in mice

Martín-de-Saavedra et al., 2013 Psychoneuroendocrinology 38: 2010—2022 Nrf2 participates in depressive disorders through an anti-inflammatory mechanism
T Nakayama
K Okimura
J Shen
Y-J Guh
TK Tamai
A Shimada
S Minou
Y Okushi
T Shimmura
Y Furukawa
N Kadofusa
A Sato
T Nishimura
M Tanaka
K Nakayama
N Shiina
N Yamamoto
AS Loudon
T Nishiwaki-Ohkawa
A Shinomiya
T Nabeshima
Y Nakane
T Yoshimura
2020
PNAS
117:
9594–9603
November 6 Danielle
Galvin
UCL
173
The neural basis of tadpole transport in poison frogs

Background papers:
Zheng Wu, Anita E. Autry, Joseph F. Bergan, Mitsuko Watabe-Uchida & Catherine G. Dulac, 2014 Nature 509: 325-330 Galanin neurons in the medial preoptic area govern parental behaviour


T Heer, CA Yovanovich, AG Pozzi DA Paz, 2008 Tissue & Cell 40: 333–342 Galanin: Presence and distribution in the brain and pituitary of Rhinella arenarum (Amphibia: Anura) during development
EK Fischer
AB Roland
NA Moskowitz
EE Tapia
K Summers
LA Coloma
LA O’Connell
2020
Proceeding
of the Royal
Society B
286:
20191084
1–10
November 13 Madhavi
Anuradha
UCL
173
Atopic dermatitis induces anxiety- and depressive-like behaviors with concomitant neuronal adaptations in brain reward circuits in mice

Background papers:
O Hashimotoa, H Kuniishi, Y Nakatake, M Yamada, K Wada, M Sekiguchi, 2020 Brain, Behavior, and Immunity 90: 319–331 Early life stress from allergic dermatitis causes depressive-like behaviors in adolescent male mice through neuroinflammatory priming


SH Park, S Jang, JE Ana, Bk Choob, HK Kim, 2020 Phytomedicine 67: 153137: 1-9 I. inflexus (Thunb.) Kudo extract improves atopic dermatitis and depressivelike behavior in DfE-induced atopic dermatitis-like disease
M Yeom
S Ahn
J-Y Oh
S-Y Kim
H Leea
D-H Hahm
H-J Park
2020
Progress in
Neuropsycho-
-pharmacology
& Biological
Psychiatry
98:
109818:
1-9
November 18 Riley
Paulsen
UCL
173
GABAergic cell transplants in the anterior cingulate cortex reduce neuropathic pain aversiveness

Background papers:
Hua et al., 2020 Nature Neuroscience 23: 854–868 General anesthetics activate a potent central pain-suppression circuit in the amygdala

Corder et al., 2019 Science 363: 276–281 An amygdalar neural ensemble that encodes the unpleasantness of pain
DL Juarez-Salinas
JM Braz
A Etlin
S Gee
V Sohal
AI Basbaum
2019
Brain
142:
2655–2669
November 20 Maddi
Bauer
UCL
173

µ-Opioid receptors in primary sensory neurons are essential for opioid analgesic effect on acute and inflammatory pain and opioid-induced hyperalgesia

Background papers:
KM Raehal and LM Bohn, 2011 Neuropharmacology 60: 58-65 The role of beta-arrestin2 in the severity of antinociceptive tolerance and physical dependence induced by different opioid pain therapeutics

CE Groer, CL Schmid, AM Jaeger, and LM Bohn 2011 Journal of Biological Chemistry 286: 31731–31741 Agonist-directed interactions with specific ß-arrestins determine µ-opioid receptor trafficking, ubiquitination, and dephosphorylation

J Sun
S-R Chen
H Chen
H-L Pan
2019
J Physiology
353:
147-165
November 26-27 Thanksgiving Pilgrims 1622 1:
eat-
sleep
Molecular Mechanisms of Affect Take Home Messages

Useful background papers:

Search for papers:

Pub Med

Use these sources to retrieve papers online

Science Direct

Journals:
Ann NY Acad Sci
Behav Neurosci
Biological Psychiatry
Brain Res Bull
Endocrinol
Euro J Neurosci
Exp Neurol
J Comp Neurol
Int J Neuropsychopharmacol
J Neurosci
Nature
Neurobiol Disease
Neurochem Res
Neuro Image
Neuron

Neuro pharmacol
Neuroscience
Pain
PNAS
Prog Neuro- Psycho pharm Biol Psych
Psycho pharmacol

Next Semester (Spring 2017): Decision Making during Depression
Last Semester (Spring 2016): Optogenetics in the Nucleus Accumbens